(Black Press Media file photo)

Vaccine against fentanyl shows promising results in rats: U.S. study

Rats chose food more times instead of fentanyl after receiving the vaccine treatment

A vaccine against fentanyl addiction is showing promising results in a recent study.

Research published in the American journal Neuropsychopharmacology last week found that a fentanyl antigen (an antigen triggers the production of antibodies) combined with a type of tetanus vaccine decreased drug-taking behaviour in rats and increased food choices, according to a news release.

British Columbia reported more than 1,300 illicit drug overdose deaths related to fentanyl in 2018, an increase of seven per cent from 2017.

“More effective and readily available treatments for opioid use disorder are needed to tackle the current crisis,” said lead authors Kim Janda, a professor at Scripps Research in San Diego, and Dr. Matthew Banks of the Virginia Commonwealth University School of Medicine.

READ MORE: Health Canada tightens marketing requirements for opioid prescriptions

“One strategy includes using opioid-targeted vaccines to elicit antibody production by the host’s immune system that recognize and block the passage of a specific opioid into the brain and peripheral organs/tissue.”

The study focused on the rats’ behavioural patterns and the number of times they chose fentanyl injections or food.

Before the treatment, rats chose a large amount of fentanyl, but within four weeks of being vaccinated, the number of times they chose the drug decreased.

The effectiveness of the vaccine has not been studied in humans.



joti.grewal@bpdigital.ca

Like us on Facebook and follow us on Twitter

Just Posted

Northern B.C.’s Ridley coal terminal sold, Canada divests, First Nations to own portion

Ten per cent of shares transferred to the Lax Kw’alaams Band and the Metlakatla First Nation

Haida artist Derek Edenshaw helps Rupert spruce up city

A giant kraken, painted by local artists under Edenshaw’s tutelage, is now on display

Haida Gwaii teacher denied paid bereavement travel leave

Arbitrator sides with B.C. Teachers Federation in dispute over funeral trip

Skeena mainstem closed to recreational sockeye

Escapements expected to be below 800,000 threshold

Rainbow Yarnbombing takes over

Haida Gwaii Knitting Group surprise the islands

‘Bad choices make good stories’: Margaret Trudeau brings her show to Just for Laughs

Trudeau says over the decades she has been suicidal, manic, depressed

VIDEO: Wolf spotted swimming ashore on northern Vancouver Island

Island wolf population estimated at under 150 in 2008, says VI-Wilds

Diversity a Canadian strength, Trudeau says of Trump tweets at congresswomen

Trudeau avoided using Trump’s name when he was asked about the president’s Twitter comments

B.C. couple bring son home from Nigeria after long adoption delay

Kim and Clark Moran of Abbotsford spent almost a year waiting to finalize adoption of Ayo, 3

Garneau ‘disappointed’ in airlines’ move against new passenger bill of rights

New rules codified compensation for lost luggage, overbooked flights

Mercury tops out on top of the world: Alert in Nunavut warmer than Victoria

It’s the latest anomaly in what’s been a long, hot summer across the Arctic

Canadian is detained in China on drug allegations: Chinese government

Detention of a Canadian in China comes as part a diplomatic dispute triggered by arrest of Huawei exec Meng Wanzhou

Too much time on social media can hurt teens’ mental health: study

Researchers conducted a four-year survey of more than 3,800 adolescents between Grades 7 and 11

Advocates want charges in horse deaths during Calgary Stampede chuckwagon races

Chuckwagon races are a nightly spectacle during the Stampede, a 10-day annual celebration of western life

Most Read